Andy Murray fought until the end, he came back from two sets down but eventually lost to Bautista Agut. John Isner is the first high-profile victim, while Nadal and Federer had straight-sets victories.
ATP Australian Open
Round Of 128
(2) Rafael Nadal d. (WC) James Duckworth 64 63 75
(3) Roger Federer d. Denis Istomin 63 64 64
(5) Kevin Anderson d. Adrian Mannarino 63 57 62 61
(6) Marin Cilic d. Bernard Tomic 62 64 76
Reilly Opelka d. (9) John Isner 76 76 67 76
(10) Karen Khachanov d. Peter Gojowczyk 36 63 64 62
Tomas Berdych d. (13) Kyle Edmund 63 60 75
(14) Stefanos Tsitsipas d. Matteo Berrettini 67 64 63 76
(18) Diego Schwartzman d. (Q) Rudolf Molleker 61 63 46 60
(19) Nikoloz Basilashvili d. (Q) Christopher Eubanks 64 46 76 63
(20) Grigor Dimitrov d. (PR) Janko Tipsarevic 46 63 61 64
(22) Roberto Bautista Agut d. (PR) Andy Murray 64 64 67 67 62
(26) Fernando Verdasco d. (Q) Miomir Kecmanovic 76 63 63
(27) Alex de Minaur d. Pedro Sousa 64 75 64
(30) Gael Monfils d. Damir Dzumhur 60 64 60
Andreas Seppi d. (31) Steve Johnson 64 46 64 63
Radu Albot d. Michael Mmoh 36 63 64 62
Pablo Cuevas d. Dusan Lajovic 64 75 61
Matthew Ebden d. Jan-Lennard Struff 16 64 63 64
(Q) Daniel Evans d. (Q) Tatsuma Ito 75 61 76
Thomas Fabbiano d. (WC) Jason Kubler 64 76 26 63
Taylor Fritz d. Cameron Norrie 63 76 62
Robin Haase d. Guillermo Garcia-Lopez 75 64 75
Denis Kudla d. (WC) Marc Polmans 57 16 62 63 62
(Q) Henri Laaksonen d. Mirza Basic 64 76 46 63
Mackenzie McDonald d. Andrey Rublev 64 64 26 64
John Millman d. Federico Delbonis 63 36 76 62
Yoshihito Nishioka d. Tennys Sandgren 64 765 46 64
Jordan Thompson d. Feliciano Lopez 61 76 63
Frances Tiafoe d. (Q) Prajnesh Gunneswaran 76 63 63
(Q) Stefano Travaglia d. Guido Andreozzi 67 62 63 62
(Q) Viktor Troicki d. Roberto Carballes Baena 61 16 26 61 64
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